CIM® TECHNOLOGY > CIM® Tube Monolithic Columns

CIM® Tube Monolithic Columns (Ready-to-Use Columns)

Ready-to-Use CIM® Tube Monolithic Columns are based on the same technology as CIM® Disks but have a different geometry. The tube geometry enables a reproducible and uniform flow profile through the monolith and has the advantage that the achieved resolution is comparable to the axial flow disk columns. (This is due to the flow-unaffected hydrodynamic characteristics of monoliths.) The thickness of the tube does not influence or decrease the separation power of the column despite an increase in the linear velocity from the outer part of the tube toward the inner part.

Disk Vs Tube Flow   



CIM® Tube Housing

The design of the housing forces the liquid to flow in a radial direction. The mobile phase entering the tube monolithic column is directed into a helical groove drilled inside the housing body, which distributes mobile phase over the entire outer surface of the monolith. The construction of the helical groove forces the mobile phase through the porous monolithic annulus and into the hollow center of the tube. The mobile phase from the outer surface of the CIM® Tube is collected in the center of the cylindric tube. The actual sample separation process takes place in the channels inside the monolith tube wall (PDF 146 KB).

The CIM® Tube Monolithic Columns are chracterised by low dead volume, excellent sample distribution and simple handling. They can be easily connected to any LC/HPLC system by means of suitable connectors.

Since the characteristics of the monolith are flow independent, the resolution on a radial monolithic column is equal to that of axial monolithic column despite a significant upgrade in linear velocity through the monolithic bed due to a cylinder thickness.