PRODUCTS > CIM® Industrial Columns

CIM® Protein G-8f mL Tube Monolithic Column

Cat. No.: 437.1011

General Description:

CIM® protein G column binds all Immunoglobulins G, including IgG3 class, which is not the case with Protein A columns. It is less resistant and somewhat higher priced than CIM® Protein A column. In comparison to Protein A, the range of polyclonal IgGs that bind strongly to Protein G is much wider and adsorption takes place over a wide pH range.

Learn more on CIM® Tube technology >>

Features and Benefits:

  • Flow unaffected resolution
Extremely fast separations speed up method development and decrease costs. Speed also enables in-process control and analytics.
  • High dynamic binding capacity
High binding capacity, even for large molecules, boost productivity even to 10-fold!
  • High throughput at low pressure drop
High flow rates can be achieved at moderate pressure drops- no need for expensive equipment (pumps).
  •  Same material and design accross all products
Same material and design accross all sizes, enable easy scale-up from analytical, semi-prep and industrial scale.

Dimensions and Operating Conditions:

Monolith dimensions
  • Outer diameter, Do: 15.0 mm
  • Inner diameter, Di: 6.5 mm
  • Length, L: 56.0 mm
  • Bed volume, V: 8.0 mL
Operating conditions
  • Flow rates: up to 400 mL/min (uav = 1340 cm/h)
    WARNING: Reversing the flow direction can seriously damage the column!
  • Pressure: up to 20 bar (2 Mpa)
  • Temperature: 4 °C (39 °F) to 40 °C (104 °F)
  • Recommended Ph:
    working range: 2–11
    cleaning-in-place: 2-13

CHEMISTRIES
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